What is the initial setting for tidal volume (VT) for infants?

The recommended initial setting for tidal volume (VT) in infants is typically in the range of 4 to 6 mL/kg. This value considers the physiological size and lung capacity of infants, who require lower tidal volumes compared to older children and adults due to their smaller lung volumes and increased susceptibility to lung injury. Setting the tidal volume within this range helps to ensure adequate ventilation while minimizing risks such as barotrauma and volutrauma, which can occur from excessive tidal volumes.

Using this range incorporates essential principles of mechanical ventilation in neonates where careful attention to lung protection and adequate gas exchange is paramount. Adjustments in tidal volume may be made based on the infant's clinical status and response to ventilation, but the initial recommendation of 4 to 6 mL/kg serves as a sound basis for initiating ventilatory support.