What typical mean airway pressure values are seen in patients with obstructive disease?

In patients with obstructive lung diseases, such as asthma or chronic obstructive pulmonary disease (COPD), mean airway pressure values typically range from 10 to 20 cmH2O. This range reflects the increased work of breathing and elevated airway resistance associated with these conditions.

During mechanical ventilation, the aim is to set pressures that help maintain adequate oxygenation and ventilation while minimizing the risk of further airway obstruction or barotrauma. Mean airway pressure is influenced by factors like peak inspiratory pressure, positive end-expiratory pressure (PEEP), and the duration of inspiration and expiration. In obstructive diseases, airflow limitation can lead to prolonged expiration, which can also contribute to elevated mean airway pressures, but they generally fall within the 10 to 20 cmH2O range to avoid excessive pressure while ensuring effective ventilation.

This understanding helps clinicians tailor ventilatory settings to optimize patient outcomes and support respiratory mechanics in those with obstructive lung diseases.